Analytical Data
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基因名
RSC1A1
- Application
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别名
RSC1A1; Regulatory solute carrier protein family 1 member 1; Transporter regulator RS1; hRS1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92681
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表达区间
1-617 aa
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氨基酸序列
MSSLPTSDGF NHPARSSGQS PDVGNPMSLA RSVSASVCPI KPSDSDRIEP KAVKALKASA EFQLNSEKKE HLSLQDLSDH ASSADHAPTD QSPAMPMQNS SEEITVAGNL EKSAERSTQG LKFHLHTRQE ASLSVTSTRM HEPQMFLGEK DWHPENQNLS QVSDPQQHEE PGNEQYEVAQ QKASHDQEYL CNIGDLELPE ERQQNQHKIV DLEATMKGNG LPQNVDPPSA KKSIPSSECS GCSNSETFME IDTAQQSLVT LLNSTGRQNA NVKNIGALDL TLDNPLMEVE TSKCNPSSEI LNDSISTQDL QPPETNVEIP GTNKEYGHYS SPSLCGSCQP SVESAEESCP SITAALKELH ELLVVSSKPA SENTSEEVIC QSETIAEGQT SIKDLSERWT QNEHLTQNEQ CPQVSFHQAI SVSVETEKLT GTSSDTGREA VENVNFRSLG DGLSTDKEGV PKSRESINKN RSVTVTSAKT SNQLHCTLGV EISPKLLAGE EDALNQTSEQ TKSLSSNFIL VKDLGQGIQN SVTDRPETRE NVCPDASRPL LEYEPPTSHP SSSPAILPPL IFPATDIDRI LRAGFTLQEA LGALHRVGGN ADLALLVLLA KNIVVPT
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分子量
66.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Research on RSC1A1 (Regulator of Chromatin Condensation 1A1) recombinant protein has garnered significant attention due to its role in chromatin dynamics and gene regulation. RSC1A1 is implicated in various cellular processes, including transcriptional regulation, DNA repair, and cell cycle progression. Its ability to interact with chromatin remodeling complexes positions it as a pivotal player in maintaining chromosomal integrity and facilitating the expression of genes necessary for development and cellular response to environmental stimuli. Alterations in RSC1A1 expression have been associated with several diseases, including cancer, highlighting its potential as a biomarker and therapeutic target. The generation of RSC1A1 recombinant protein allows researchers to study its biochemical properties and functional dynamics in controlled settings. By utilizing techniques such as affinity purification and structural analysis, scientists aim to elucidate the mechanisms by which RSC1A1 influences chromatin structure and function. Furthermore, understanding RSC1A1’s interactions with other nuclear proteins and its regulatory pathways may inform the development of novel strategies to modulate gene expression in disease contexts. Overall, the investigation of RSC1A1 recombinant protein is crucial for advancing our understanding of chromatin biology and uncovering new avenues for therapeutic intervention in chromatin-related pathologies.
