Analytical Data
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基因名
DRAXIN
- Application
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别名
DRAXIN;C1orf187;Draxin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NBI3
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表达区间
26-349aa
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氨基酸序列
GALAPGTPARNLPENHIDLPGPALWTPQASHHRRRGPGKKEWGPGLPSQAQDGAVVTATRQASRLPEAEGLLPEQSPAGLLQDKDLLLGLALPYPEKENRPPGWERTRKRSREHKRRRDRLRLHQGRALVRGPSSLMKKAELSEAQVLDAAMEESSTSLAPTMFFLTTFEAAPATEESLILPVTSLRPQQAQPRSDGEVMPTLDMALFDWTDYEDLKPDGWPSAKKKEKHRGKLSSDGNETSPAEGEPCDHHQDCLPGTCCDLREHLCTPHNRGLNNKCFDDCMCVEGLRCYAKFHRNRRVTRRKGRCVEPETANGDQGSFINV
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分子量
52.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Draxin is a protein initially identified as an axon guidance cue involved in central nervous system development. It plays a crucial role in the regulation of neuronal orientation and connectivity, influencing the growth of axons and the formation of synapses. Beyond its functions in neural development, recent studies have suggested that Draxin may also be involved in various physiological processes, including embryogenesis and tissue repair. Due to its dual role in both the nervous system and developmental biology, Draxin has garnered attention as a potential therapeutic target for neurological disorders and regenerative medicine. Understanding the structure and function of recombinant Draxin protein can facilitate the exploration of its interactions with other molecular entities, thus providing insights into its mechanisms and potential applications in treating conditions such as spinal cord injuries or neurodegenerative diseases. The advancement in recombinant protein technology has enabled the production of Draxin in sufficient quantities for functional assays and structural studies, laying the groundwork for future investigations into its biological significance and therapeutic potential. Researchers are particularly interested in characterizing the protein's binding interactions and signaling pathways to elucidate its role in cell migration and differentiation. Furthermore, as the field of molecular neuroscience continues to evolve, the study of Draxin could lead to new approaches in understanding and manipulating neural circuitry, paving the way for innovative strategies in regenerative therapies.












