Analytical Data
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Gene name
TBX20
- Application
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Alternative Names
T-box 20; T-box protein 20; T-box transcription factor TBX20; Tbox 20; tbx20; TBX20_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UMR3
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Expression Region
1-447 aa
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AA Sequence
MEFTASPKPQ LSSRANAFSI AALMSSGGSK EKEATENTIK PLEQFVEKSS CAQPLGELTS LDAHGEFGGG SGSSPSSSSL CTEPLIPTTP IIPSEEMAKI ACSLETKELW DKFHELGTEM IITKSGRRMF PTIRVSFSGV DPEAKYIVLM DIVPVDNKRY RYAYHRSSWL VAGKADPPLP ARLYVHPDSP FTGEQLLKQM VSFEKVKLTN NELDQHGHII LNSMHKYQPR VHIIKKKDHT ASLLNLKSEE FRTFIFPETV FTAVTAYQNQ LITKLKIDSN PFAKGFRDSS RLTDIERESV ESLIQKHSYA RSPIRTYGGE EDVLGDESQT TPNRGSAFTT SDNLSLSSWV SSSSSFPGFQ HPQSLTALGT STASIATPIP HPIQGSLPPY SRLGMPLTPS AIASSMQGSG PTFPSFHMPR YHHYFQQGPY AAIQGLRHSS AVMTPFV
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Molecular Weight
49.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBX20 is a member of the T-box family of transcription factors, which play critical roles in the development and differentiation of various tissues, particularly in the heart and skeletal muscle. Its significance has come to the forefront due to its involvement in congenital heart diseases and its regulatory functions in cardiomyocyte proliferation and differentiation. Abnormal expression of TBX20 has been linked to both congenital and acquired heart conditions, highlighting the importance of understanding its biological mechanisms. Recent studies have shown that TBX20 interacts with various signaling pathways, influencing gene expression related to cardiac development and function. This has led to increased interest in TBX20 recombinant protein for potential therapeutic applications, such as gene therapy and regenerative medicine. By producing and studying TBX20 recombinant protein, researchers aim to gain insights into its structural and functional properties, the molecular pathways it regulates, and its potential role in heart disease treatments. This research could pave the way for novel strategies aimed at modulating TBX20 activity for therapeutic benefits in cardiovascular diseases. Overall, the study of TBX20 recombinant protein is crucial for elucidating its functional roles in cardiac biology and for exploring new avenues in the treatment of heart-related disorders.
