Analytical Data
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Gene name
TFAP4
- Application
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Alternative Names
Transcription factor AP-4. Activating enhancer-binding Protein 4. Class C basic helix-loop-helix Protein 41. bHLHc41
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q01664
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Expression Region
1-338 aa
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AA Sequence
MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEKQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASDSDAMDQSREEPSGDGELP
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Molecular Weight
65.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TFAP4, or Transcription Factor AP-4, is a crucial member of the AP-1 superfamily of transcription factors, and it plays a significant role in various biological processes, including cell proliferation, differentiation, and apoptosis. Its expression is particularly evident in specific tissues and during developmental stages, suggesting that it is essential for normal physiological functions. Research has indicated that TFAP4 may be involved in tumorigenesis and various diseases, making it a potential target for therapeutic interventions. The recombinant protein of TFAP4 is engineered to study its structure-function relationships, regulatory mechanisms, and interactions with other biomolecules. By producing TFAP4 as a recombinant protein, researchers aim to elucidate its role in gene expression regulation and cellular signaling pathways. This foundational understanding is critical for exploring TFAP4's potential in clinical applications, including cancer therapy and regenerative medicine. As the interest in target-specific therapies grows, characterizing TFAP4 through recombinant techniques can provide insights into its function and contribute to the development of novel therapeutic strategies.
