Analytical Data
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基因名
TNIP2
- Application
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别名
TNIP2；ABIN2；FLIP1；TNFAIP3-interacting Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NFZ5
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表达区间
1-429aa
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氨基酸序列
MSRDPGSGGW EEAPRAAAAL CTLYHEAGQR LRRLQDQLAA RDALIARLRA RLAALEGDAA PSLVDALLEQ VARFREQLRR QEGGAAEAQM RQEIERLTER LEEKEREMQQ LLSQPQHERE KEVVLLRRSM AEGERARAAS DVLCRSLANE THQLRRTLTA TAHMCQHLAK CLDERQHAQR NVGERSPDQS EHTDGHTSVQ SVIEKLQEEN RLLKQKVTHV EDLNAKWQRY NASRDEYVRG LHAQLRGLQI PHEPELMRKE ISRLNRQLEE KINDCAEVKQ ELAASRTARD AALERVQMLE QQILAYKDDF MSERADRERA QSRIQELEEK VASLLHQVSW RQDSREPDAG RIHAGSKTAK YLAADALELM VPGGWRPGTG SQQPEPPAEG GHPGAAQRGQ GDLQCPHCLQ CFSDEQGEEL LRHVAECCQ
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TNIP2, or TNF receptor-associated factor 3-interacting protein 2, is a crucial regulatory protein that plays a significant role in modulating inflammatory responses and immune signaling pathways. It is primarily known for its interactions with tumor necrosis factor (TNF) receptor-associated factors, thereby influencing processes such as cell survival, apoptosis, and the activation of immune cells. Dysregulation of TNIP2 has been implicated in various pathologies, including autoimmune diseases, cancer, and inflammatory disorders. Recent studies have highlighted its potential as a therapeutic target, given its ability to modulate key signaling pathways and inflammatory responses. The research on recombinant TNIP2 protein focuses on its structural characterization, functional analysis, and interaction with other proteins within signaling networks. By producing and studying recombinant TNIP2, scientists aim to elucidate its biological functions, determine the consequences of its dysregulation, and explore its potential as a biomarker or therapeutic agent in various diseases. Understanding TNIP2's mechanisms of action not only advances the field of immunology but also provides insights into novel therapeutic strategies for managing related diseases.
