Analytical Data
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基因名
TNFSF12
- Application
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别名
TNFSF12；APO3L；DR3LG；Tumor necrosis factor ligand superfamily member 12
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43508
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表达区间
93-249aa
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氨基酸序列
RSAPKGRKTRARRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEEARINSSS PLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLDLLVDGVLALRCL EEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFLTY FGLFQVH
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分子量
17 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TNFSF12, also known as Tumor Necrosis Factor Superfamily Member 12 or Apo3L, is a cytokine that plays a crucial role in immune regulation and inflammation. Research into TNFSF12 has gained momentum due to its involvement in various pathological conditions, including autoimmune diseases, cancer, and metabolic disorders. This protein acts through its receptor, TNFRSF25, to promote cell survival, proliferation, and the activation of various immune cells, highlighting its potential as a therapeutic target. Scientists are particularly interested in understanding the molecular mechanisms behind TNFSF12's actions, exploring its role in maintaining immune homeostasis and its potential in enhancing antitumor immunity. With the ongoing advancements in recombinant protein technologies, the production of TNFSF12 in a laboratory setting allows for detailed functional analysis and the development of novel treatments. Investigations into the structure and function of TNFSF12 are essential for elucidating its signaling pathways and therapeutic applications, potentially leading to innovative strategies for modulating immune responses in diseases such as cancer and autoimmune disorders. Overall, this area of research holds promise for uncovering new insights into immune system regulation and improving therapeutic interventions.
