Analytical Data
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基因名
FFAR2
- Application
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别名
FFAR2；FFA2；GPCR43；GPR43；Free fatty acid receptor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15552
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表达区间
1-330aa
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氨基酸序列
MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
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分子量
37.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FFAR2 (Free Fatty Acid Receptor 2), also known as GPR43, is an important G protein-coupled receptor primarily expressed in immune cells, adipose tissue, and the gastrointestinal tract. Research into FFAR2 has gained momentum due to its role in regulating metabolic processes, inflammation, and immune responses. It is activated by short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate, which are produced during the fermentation of dietary fibers by gut microbiota. This interaction suggests that FFAR2 is a critical link between diet, gut microbiota, and health. Understanding the mechanisms through which FFAR2 functions could unveil potential therapeutic targets for metabolic disorders, obesity, and inflammatory diseases. Additionally, FFAR2's contribution to gut-brain communication highlights its relevance in neuroinflammation and neurodegenerative conditions. As researchers explore FFAR2 through recombinant protein studies, the aim is to elucidate its signaling pathways and physiological roles, with the hope of harnessing this receptor's potential to improve health outcomes linked to diet and chronic diseases.
