Analytical Data
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基因名
GJA10
- Application
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别名
GJA10; CX62; Gap junction alpha-10 protein; Connexin-62; Cx62
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q969M2
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表达区间
1-543aa
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氨基酸序列
MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSKTMWQIPQPRQLEVDPSNGKKDWSEKDQHSGQLHVHSPCPWAGSAGNQHLGQQSDHSSFGLQNTMSQSWLGTTTAPRNCPSFAVGTWEQSQDPEPSGEPLTDLHSHCRDSEGSMRESGVWIDRSRPGSRKASFLSRLLSEKRHLHSDSGSSGSRNSSCLDFPHWENSPSPLPSVTGHRTSMVRQAALPIMELSQELFHSGCFLFPFFLPGVCMYVCVDREADGGGDYLWRDKIIHSIHSVKFNS
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分子量
88.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GJA10, a member of the gap junction protein family, plays a crucial role in intercellular communication by facilitating the transfer of ions and small molecules between adjacent cells. Research into GJA10 has gained prominence due to its potential implications in various physiological and pathological processes. This protein is particularly significant in the context of human reproductive health, where its expression in the testes and its role in spermato-genesis have drawn considerable attention. Additionally, alterations in GJA10 expression have been linked to several diseases, including infertility and certain types of cancer. Its function in cell signaling and tissue homeostasis highlights its importance in maintaining cellular functions and responses to environmental changes. The investigation of GJA10 recombinant protein is pivotal for understanding its structural properties, functional mechanisms, and interactions with other cellular components. By utilizing recombinant DNA technology, researchers can produce this protein in sufficient quantities for further functional and structural studies. Such investigations are crucial not only for elucidating the basic biology of gap junction communication but also for exploring potential therapeutic targets in diseases associated with gap junction dysfunction. Understanding GJA10 at a molecular level opens avenues for innovative strategies in regenerative medicine and cancer treatment, making it an essential focal point in contemporary biomedical research.
