Analytical Data
-
Gene name
PTPRT
- Application
-
Alternative Names
Receptor-type tyrosine-protein phosphatase rho (RPTP-rho) (R-PTP-T) (KIAA0283) Short name:
-
Species
Human
-
Source
Baculovirus
-
Tag
N- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
O14522
-
Expression Region
26-747aa
-
Molecular Weight
81.3
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTPRT (Protein Tyrosine Phosphatase Receptor Type T) is a member of the receptor protein tyrosine phosphatase family, which plays a crucial role in various cellular processes, including cell growth, differentiation, and signal transduction. Abnormalities in PTPRT expression or function have been implicated in several diseases, particularly cancers, as they can disrupt normal signaling pathways that are critical for maintaining cellular homeostasis. Research into the recombinant expression of PTPRT has gained traction due to its potential as a therapeutic target and biomarker in oncology. By producing recombinant PTPRT proteins, scientists can investigate the enzyme's structural properties, elucidate its functional roles in cellular signaling, and explore its interactions with various substrates. This research not only enhances our understanding of its mechanisms in normal physiology but also provides insights into its contributions to tumorigenesis and progression. Furthermore, the ability to engineer PTPRT may facilitate the development of novel therapeutic strategies, including the design of inhibitors or compounds that can modulate its activity. Thus, the study of PTPRT recombinant proteins is a pivotal area of research with significant implications for understanding cancer biology and developing targeted treatments.
