Analytical Data
-
基因名
CCL16
- Application
-
别名
SCYA16; SCYL4; LEC; HCC4; LMC; LCC1; CKb12; Mtn1; CC-4; Monotactin-1; IL-10-inducible chemokine; Liver-expressed chemokine; Lymphocyte and monocyte chemoattractant
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O15467
-
表达区间
Ala20~Gln120
-
分子量
15kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCL16, also known as liver and activation-regulated chemokine (LARC), is a notable member of the CC chemokine family, primarily recognized for its role in immune responses and inflammation. As a chemokine, CCL16 is involved in the recruitment of immune cells, particularly Th2 cells and eosinophils, to sites of inflammation, making it critical in various physiological and pathological processes, including allergic reactions, infectious diseases, and autoimmune conditions. Research indicates that CCL16 may play a significant role in modulating inflammatory responses, and its expression is often upregulated in conditions like asthma, chronic obstructive pulmonary disease (COPD), and certain cancers. The recombinant protein of CCL16 has gained attention for its potential applications in both basic research and therapeutic development. By studying the biochemical properties and functional mechanisms of CCL16, scientists aim to develop novel strategies to target inflammatory diseases, improve understanding of immune system dynamics, and explore its potential as a biomarker or therapeutic agent. The production and characterization of recombinant CCL16 protein facilitate a deeper investigation into its biological functions, interactions with receptors such as CCR4 and CCR8, and its influence on immune cell signaling pathways. This research holds promise for enhancing our knowledge of chemokines in immune regulation and offers insights into new treatment avenues for chronic inflammatory diseases.
