Analytical Data
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Gene name
RARb
- Application
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Alternative Names
HAP; NR1B2; RRB2; RAR-epsilon; HBV-activated protein; Nuclear receptor subfamily 1 group B member 2
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P10826
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Expression Region
Leu205~Ser451
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Molecular Weight
31kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RARb, or Retinoic Acid Receptor beta, is a member of the nuclear receptor superfamily that plays a crucial role in mediating the effects of retinoic acid, a metabolite of vitamin A. This receptor is involved in various biological processes, including cell differentiation, growth regulation, and apoptosis. Studies have shown that RARb is significantly implicated in the pathology of several cancers, particularly in the context of tumor suppressor functions. Abnormal expression of RARb has been linked to tumor progression and poor prognosis in various malignancies, highlighting the importance of understanding its regulatory mechanisms and downstream signaling pathways. The research on RARb recombinant proteins aims to explore their functional roles and interactions in cellular contexts, providing insights into how RARb modulation might offer novel therapeutic strategies. By generating and studying RARb recombinant proteins in vitro and in vivo, scientists can investigate their structures, binding affinities, and effects on target genes. This research can contribute to the development of RARb-targeted therapies that could restore its function in cancer treatment and other diseases associated with retinoic acid signaling dysregulation. Overall, the study of RARb recombinant proteins is pivotal for unraveling the complexities of retinoic acid signaling and its implications in health and disease.
