Analytical Data
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基因名
OCTN1
- Application
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别名
SLC22A4; ETT; UT2H; Solute Carrier Family 22 Member 4; ET transporter
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H015
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表达区间
Leu42~Lys141
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分子量
18kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OCTN1 (Organic Cation Transporter Novel 1), also known as SLC22A4, is a member of the solute carrier family responsible for the transport of cationic and zwitterionic compounds across cellular membranes. The interest in OCTN1 has grown due to its critical role in pharmacokinetics, influencing the absorption, distribution, metabolism, and excretion of various drugs. Deficiencies or mutations in the OCTN1 gene are linked to several health issues, including primary carnitine deficiency, which can lead to severe metabolic disorders. Moreover, OCTN1 is believed to play a role in the transport of nutrients and harmful substances, affecting inflammatory responses and the development of certain diseases. Understanding the function and mechanism of OCTN1 is essential for enhancing drug efficacy and safety. Recent advancements in recombinant protein techniques have enabled the production of OCTN1 in heterologous systems, facilitating detailed studies of its structural and functional properties. Characterization of OCTN1 through recombinant protein methods helps elucidate substrate specificity, transport kinetics, and regulatory mechanisms, providing insights into how variations in OCTN1 activity might impact health and disease. Therefore, research on OCTN1 recombinant protein is pivotal in pharmacology and therapeutics, aiming to identify potential drug candidates and develop targeted therapies that consider individual genetic variations in transporter functions.
