Analytical Data
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Gene name
XPO3
- Application
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Alternative Names
XPOT; Exportin,tRNA(Nuclear Export Receptor For tRNAs)
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
D3ZZ62
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Expression Region
Met1~Lys269
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Molecular Weight
32 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
XPO3, also known as exportin 3, is a member of the karyopherin superfamily involved in the nucleocytoplasmic transport of macromolecules. It plays a critical role in the export of specific proteins and RNA from the nucleus to the cytoplasm, which is essential for various cellular processes, including cell proliferation, gene expression, and stress responses. Dysfunction of XPO3 has been linked to several diseases, including cancer and viral infections, where aberrant nuclear transport can lead to the misregulation of key regulatory proteins. Research on XPO3 recombinant proteins focuses on elucidating its structure-function relationship, as well as its interaction with cargo molecules and other nuclear transport factors. Understanding XPO3's mechanisms can provide insights into its potential as a therapeutic target and contribute to the development of novel cancer treatments and antiviral strategies. Additionally, investigating the role of XPO3 in cellular responses to stress can help clarify its involvement in cellular signaling pathways and its implications in developmental biology and disease mechanisms. Given the importance of nuclear transport in maintaining cellular homeostasis, the study of XPO3 represents a significant area of research within cell biology and biomedicine.
