Analytical Data
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基因名
XPO3
- Application
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别名
XPOT; Exportin,tRNA(Nuclear Export Receptor For tRNAs)
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
D3ZZ62
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表达区间
Met1~Lys269
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
XPO3, also known as exportin 3, is a member of the karyopherin superfamily involved in the nucleocytoplasmic transport of macromolecules. It plays a critical role in the export of specific proteins and RNA from the nucleus to the cytoplasm, which is essential for various cellular processes, including cell proliferation, gene expression, and stress responses. Dysfunction of XPO3 has been linked to several diseases, including cancer and viral infections, where aberrant nuclear transport can lead to the misregulation of key regulatory proteins. Research on XPO3 recombinant proteins focuses on elucidating its structure-function relationship, as well as its interaction with cargo molecules and other nuclear transport factors. Understanding XPO3's mechanisms can provide insights into its potential as a therapeutic target and contribute to the development of novel cancer treatments and antiviral strategies. Additionally, investigating the role of XPO3 in cellular responses to stress can help clarify its involvement in cellular signaling pathways and its implications in developmental biology and disease mechanisms. Given the importance of nuclear transport in maintaining cellular homeostasis, the study of XPO3 represents a significant area of research within cell biology and biomedicine.
