Analytical Data
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基因名
DOC2b
- Application
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别名
DOC2BL; Double C2-like domain-containing protein beta
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14184
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表达区间
Gly173~Asp412
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分子量
31kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DOC2b, or document 2b, is a protein that plays a critical role in neuronal communication and synaptic function. As part of the DOC family, DOC2b is involved in calcium-dependent exocytosis, influencing neurotransmitter release in neurons. Research into DOC2b has been driven by its potential implications in understanding various neurological disorders, including autism, schizophrenia, and other synaptic dysfunctions. Studies have shown that DOC2b is associated with synaptic vesicles and interacts with other proteins to facilitate the docking and fusion of vesicles at the synapse in response to calcium influx. Given the importance of synaptic plasticity in learning and memory, investigating the functional mechanisms of DOC2b may offer insights into its role in these processes. Advances in molecular biology and biochemistry have allowed for the exploration of DOC2b's structure, function, and interaction networks, paving the way for potential therapeutic strategies targeting synaptic modulation. Furthermore, the study of DOC2b can also contribute to the broader understanding of calcium signaling in excitable cells. As researchers continue to elucidate the complexities of DOC2b, it remains a significant focus within neuroscience, with the hope of unraveling new avenues for treating synaptic-related disorders.












