Analytical Data
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基因名
GOT2
- Application
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别名
Fatty acid-binding protein Short name: FABP-1 Glutamate oxaloacetate transaminase 2 Kynurenine aminotransferase 4 Kynurenine aminotransferase IV Kynurenine--oxoglutarate transaminase 4 Kynurenine--oxoglutarate transaminase IV Plasma membrane-associated fatty acid-binding protein Short name: FABPpm Transaminase A
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种属
Bovine
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P12344
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表达区间
20-430aa
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分子量
61.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GOT2 (Glutamate Oxidoreductase 2) is a mitochondrial enzyme that plays a crucial role in the metabolic pathways of amino acids and the regulation of oxidative stress. As a member of the glutamate-dependent dehydrogenase family, GOT2 catalyzes the reversible conversion of alpha-ketoglutarate and aspartate, contributing to the TCA cycle and energy production in cells. Research into recombinant GOT2 protein has gained attention due to its potential implications in various biological processes, including neurodegenerative diseases and metabolic disorders. Understanding the structure and function of GOT2 can provide insights into its molecular mechanisms and interactions within the mitochondrial environment, revealing how alterations in its activity may influence cellular homeostasis. Furthermore, the production of recombinant GOT2 facilitates the investigation of its enzymatic properties and interactions with other cellular components, supporting the development of therapeutic strategies targeting diseases associated with aberrant glutamate metabolism. The ongoing study of GOT2 is critical, not only for comprehending its role in cellular physiology but also for exploring its potential as a biomarker or therapeutic target in conditions such as Parkinson’s disease, Alzheimer's disease, and various metabolic syndromes, where mitochondrial dysfunction is often a contributing factor.
