Analytical Data
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基因名
NCK2
- Application
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别名
Growth factor receptor-bound protein 4NCK adaptor protein 2 ;Nck-2SH2/SH3 adaptor protein NCK-beta
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43639
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表达区间
1-380aa
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分子量
58.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NCK2 (NCK adaptor protein 2) is a crucial intracellular signaling molecule that plays a significant role in various cellular processes, including cell growth, differentiation, and migration. It primarily functions as an adaptor protein, facilitating the interaction between diverse signaling pathways and membrane proteins, thus affecting cytoskeletal organization and cellular morphology. Research on NCK2 has gained prominence due to its involvement in critical biological functions and its potential link to various diseases, including cancer. The study of NCK2 recombinant proteins allows researchers to investigate its structural properties, binding interactions, and functional roles in cells. By expressing NCK2 in a recombinant form, scientists can gain insights into its signaling mechanisms and the effects of specific mutations or modifications. Understanding the biochemical and biophysical characteristics of NCK2 can pave the way for developing targeted therapeutic strategies, especially in malignancies where NCK2 is deregulated. Additionally, the exploration of NCK2's role in normal physiology could provide further elucidation of its contributions to cellular homeostasis and tissue development, making it a promising target for future research in both basic and applied biosciences.
