Analytical Data
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基因名
MRP
- Application
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种属
Chicken
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表达系统
Yeast
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标签
C- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P28318
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表达区间
1-119aa
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分子量
15.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRP (Multidrug Resistance Protein) recombinant proteins play a crucial role in understanding the mechanisms of drug resistance in cancer and other diseases. Research on MRP proteins stems from their involvement in the efflux of various substrates, including chemotherapeutic agents, which can significantly impact treatment efficacy. The identification and characterization of MRP proteins have been driven by the need to overcome drug resistance, a major hurdle in effective cancer therapy. By producing recombinant forms of these proteins, researchers can study their structure, function, and interactions at a molecular level. This approach has led to insights into how MRP proteins recognize and transport a wide range of compounds, allowing for the development of potential inhibitors that could enhance the sensitivity of cancer cells to therapies. Furthermore, understanding the genetic and biochemical pathways that regulate MRP expression can pave the way for personalized medicine strategies, where patients receive tailored treatments based on their specific genetic profiles. The research into MRP recombinant proteins not only contributes to the fundamental knowledge of cellular transport mechanisms but also holds promise for improving therapeutic outcomes in oncology and other fields affected by multidrug resistance.












