Analytical Data
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基因名
NGFIB
- Application
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别名
NGFIB；Hmr；Ngfib；Nuclear receptor subfamily 4 group A member 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P22736
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表达区间
1-598aa
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氨基酸序列
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTAL PSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASAS FKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQ LSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSP SLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPV TSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLP SKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDA GDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILR LAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDV PAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPAS CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
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分子量
92 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Nerve Growth Factor Induced Protein B (NGFIB) is a key member of the nuclear receptor superfamily that plays a critical role in various biological processes, including cell differentiation, development, and apoptosis. Initially identified as a target gene for nerve growth factor (NGF) in neuronal cells, NGFIB has been implicated in the regulation of neuroprotective and neurotrophic effects, making it significant in studies related to neurodegenerative diseases and neurological disorders. Recent research has shown that NGFIB may also influence immune responses and has potential implications in cancer biology, where it could affect tumor growth and metastasis. The recombinant production of NGFIB protein allows for detailed structural and functional studies, paving the way for potential therapeutic applications. Understanding its mechanisms of action could offer insights into developing novel strategies for treating diseases associated with NGFIB dysregulation. Additionally, NGFIB's interactions with other cellular signaling pathways highlight its multifunctional nature, making it an important target for further investigation in both basic and applied biomedical research. The ongoing exploration of NGFIB's roles across different biological contexts emphasizes the necessity of recombinant protein technology in unraveling its complex functions.
