Analytical Data
-
Gene name
ABHD5
- Application
-
Alternative Names
Abhydrolase domain-containing protein 5 Lipid droplet-binding protein CGI-58
-
Species
Human
-
Source
E. coli
-
Tag
N- His-SUMO
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8WTS1
-
Expression Region
2-349aa
-
Molecular Weight
55 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABHD5, or Abhydrolase Domain-Containing 5, is a protein critically involved in lipid metabolism, particularly in the regulation of fat storage and mobilization. It acts as a co-activator of the enzyme adipose triglyceride lipase (ATGL), which is vital for the breakdown of triglycerides into free fatty acids and glycerol. Dysregulation of ABHD5 has been associated with metabolic disorders, including obesity and insulin resistance, making it a significant target for therapeutic research. The study of recombinant ABHD5 proteins allows scientists to investigate its structure, function, and interactions at a molecular level. By generating and purifying these proteins, researchers can perform biochemical assays to elucidate ABHD5's role in lipolysis and its regulatory mechanisms. Understanding the precise functions of ABHD5 not only contributes to the fundamental knowledge of lipid metabolism but also opens up potential avenues for the development of novel interventions aimed at treating metabolic diseases. Furthermore, recombinant ABHD5 can be employed in drug screening and development processes, as identifying small molecules or compounds that modulate ABHD5 activity might provide new strategies to tackle metabolic disorders. Overall, the exploration of ABHD5 recombinant proteins is a promising frontier in the quest to better understand and manipulate lipid metabolism for therapeutic gains.
