Analytical Data
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基因名
ABHD5
- Application
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别名
Abhydrolase domain-containing protein 5 Lipid droplet-binding protein CGI-58
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WTS1
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表达区间
2-349aa
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分子量
55 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ABHD5, or Abhydrolase Domain-Containing 5, is a protein critically involved in lipid metabolism, particularly in the regulation of fat storage and mobilization. It acts as a co-activator of the enzyme adipose triglyceride lipase (ATGL), which is vital for the breakdown of triglycerides into free fatty acids and glycerol. Dysregulation of ABHD5 has been associated with metabolic disorders, including obesity and insulin resistance, making it a significant target for therapeutic research. The study of recombinant ABHD5 proteins allows scientists to investigate its structure, function, and interactions at a molecular level. By generating and purifying these proteins, researchers can perform biochemical assays to elucidate ABHD5's role in lipolysis and its regulatory mechanisms. Understanding the precise functions of ABHD5 not only contributes to the fundamental knowledge of lipid metabolism but also opens up potential avenues for the development of novel interventions aimed at treating metabolic diseases. Furthermore, recombinant ABHD5 can be employed in drug screening and development processes, as identifying small molecules or compounds that modulate ABHD5 activity might provide new strategies to tackle metabolic disorders. Overall, the exploration of ABHD5 recombinant proteins is a promising frontier in the quest to better understand and manipulate lipid metabolism for therapeutic gains.
