Analytical Data
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Gene name
DCLRE1A
- Application
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Alternative Names
(Beta-lactamase DCLRE1A)(SNM1 homolog A)(hSNM1)(hSNM1A)
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PJP8
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Expression Region
690-1040aa
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Molecular Weight
43.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DCLRE1A, also known as DNA cross-link repair 1A, is a crucial protein involved in the process of DNA repair, particularly in the context of resolving DNA structures that arise from interstrand cross-links and double-strand breaks. It plays a significant role in maintaining genomic stability and preventing genetic diseases, including cancer. The study of DCLRE1A has gained attention due to its implication in various cellular processes, such as DNA damage response, replication stress, and apoptosis. Mutations or deficiencies in DCLRE1A have been linked to specific genetic disorders, which further underscores its importance in human health. The recombinant expression of DCLRE1A allows researchers to investigate its biochemical properties, interactions with other proteins, and its role in DNA repair pathways in a controlled laboratory setting. Understanding the functional mechanisms of DCLRE1A is critical for developing new therapeutic strategies for diseases associated with defective DNA repair mechanisms. Additionally, exploring the protein's structural characteristics through recombinant technology can provide insights into its enzymatic activity and regulatory functions, paving the way for potential interventions in cancer treatment and other genetic disorders. Overall, the study of recombinant DCLRE1A represents a vital area of research in molecular biology and genetics, with significant implications for therapeutic advancements and the comprehension of cellular responses to DNA damage.
