Analytical Data
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基因名
FMR1NB
- Application
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别名
Cancer/testis antigen 37 (CT37) (Sarcoma antigen NY-SAR-35)
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N0W7
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表达区间
90-183aa
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分子量
15.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FMR1NB (Fragile X Messenger Ribonucleoprotein 1 N-terminal Binding) protein is increasingly recognized for its role in the molecular mechanisms underlying various neurological disorders, particularly Fragile X syndrome, the most common form of inherited intellectual disability. The FMR1 gene, which encodes the FMRP protein, is crucial for synaptic function and plasticity, and mutations in this gene lead to abnormal brain development and cognitive impairment. Research has shown that FMR1NB interacts with FMRP and may influence its function, thereby impacting mRNA transport and translation in neurons. Understanding the structure and dynamics of the FMR1NB protein is essential for elucidating its potential role in neurodevelopmental processes and its therapeutic implications. Investigating FMR1NB's interactions and functional pathways could provide new insights into the molecular biology of Fragile X syndrome and related disorders, paving the way for innovative interventions. As such, the characterization of FMR1NB through recombinant techniques holds promise for advancing knowledge in neurobiology, enhancing our understanding of protein interactions, and potentially guiding the development of disease-modifying therapies.
