Analytical Data
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Gene name
GDF6
- Application
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Alternative Names
GDF6；BMP13；GDF16；Growth/differentiation factor 6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6KF10
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Expression Region
336-455aa
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AA Sequence
TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
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Molecular Weight
13.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GDF6 (Growth Differentiation Factor 6) is a member of the TGF-β superfamily and plays a crucial role in various biological processes, including embryonic development, tissue differentiation, and regeneration. It is particularly important in the development of the skeletal system, where it influences chondrogenesis and bone formation. The study of recombinant GDF6 protein has garnered significant attention due to its potential therapeutic applications in regenerative medicine and orthopedics. Researchers are investigating its role in cartilage repair and bone healing, especially in conditions such as osteoarthritis and other degenerative joint diseases. Additionally, GDF6 has been implicated in the regulation of signaling pathways that govern cellular proliferation and apoptosis, making it a candidate for cancer research. The recombinant form of GDF6 allows for detailed studies of its function, interactions with other proteins, and potential impact on cellular behavior in vitro and in vivo. Understanding the molecular mechanisms underlying GDF6 activity could lead to innovative strategies for enhancing tissue regeneration and developing novel treatments for skeletal disorders. Furthermore, exploring its effects in various biological contexts can provide insights into its broader implications in health and disease. Therefore, the characterization and application of GDF6 recombinant protein represent a promising frontier in biomedical research, aiming to leverage its unique properties for therapeutic developments.
