Analytical Data
-
Gene name
Cyp3a16
- Application
-
Alternative Names
(CYPIIIA16)
-
Species
Mouse
-
Source
E. coli
-
Tag
N- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q64481
-
Expression Region
1-504aa
-
Molecular Weight
63.8 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Cyp3a16 is a member of the cytochrome P450 family, which plays a crucial role in the metabolism of various xenobiotics and endogenous substances. This enzyme has garnered significant interest due to its involvement in drug metabolism and the potential implications for pharmacogenetics and toxicology. Unlike some other cytochrome P450 enzymes that are well-characterized in humans, Cyp3a16 is primarily expressed in rodents, particularly in the liver and intestines, making it a valuable model for studying drug metabolism. Research has indicated that Cyp3a16 exhibits unique substrate specificity and can metabolize a range of compounds, including steroids and various therapeutic drugs. Understanding the biochemical properties, substrate interactions, and regulatory mechanisms of Cyp3a16 can provide insights into species differences in drug metabolism and the potential impact on drug development and safety assessments. Moreover, by producing recombinant Cyp3a16 protein, researchers can investigate its enzymatic activities in vitro, paving the way for advances in personalized medicine and the design of new pharmaceuticals that consider metabolic pathways. As such, the study of Cyp3a16 not only expands our knowledge of cytochrome P450 biology but also holds promise for improving drug efficacy and reducing adverse drug reactions in both human and veterinary medicine.
