Analytical Data
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Gene name
RRAGA
- Application
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Alternative Names
RRAGA；Ras-related GTP-binding Protein A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7L523
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Expression Region
1-247aa
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AA Sequence
MPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAQIIEADEVLLFERATFLVISHYQCKEQRDVHRFEKISNIIKQFKLSCSKLAA
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Molecular Weight
56.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RRAGA (Ras-related GTPase A) is a member of the RAS superfamily, which plays a crucial role in various cellular processes, including cell growth, differentiation, and metabolism. Research on RRAGA has garnered significant attention due to its involvement in mTOR (mechanistic target of rapamycin) signaling pathways, which are pivotal in regulating cellular responses to nutrient availability and stress. Dysregulation of mTOR signaling has been linked to a range of diseases, including cancer, obesity, and metabolic disorders. Furthermore, RRAGA has been identified as a key regulator of autophagy, a cellular degradation process that is essential for maintaining cellular homeostasis. The study of RRAGA and its interactions with other proteins offers potential insights into therapeutic targets for diseases where mTOR signaling and autophagy are disrupted. As a result, recombinant proteins of RRAGA are being explored to elucidate its structural and functional properties, facilitating a better understanding of its role in cellular signaling pathways. This research not only highlights the biological significance of RRAGA but also provides a foundation for developing novel interventions aimed at modulating its activity in relevant disease contexts.
