Analytical Data
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基因名
GPR83
- Application
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别名
GPR83; GPR72; KIAA1540; Probable G-protein coupled receptor 83; G-protein coupled receptor 72
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NYM4
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表达区间
1-423aa
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氨基酸序列
MVPHLLLLCLLPLVRATEPHEGRADEQSAEAALAVPNASHFFSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLLSSKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDRPPSPVPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGKTDLSSVEPIVTMS
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分子量
48.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPR83, or G protein-coupled receptor 83, is an evolutionary conserved receptor that has garnered attention in recent years due to its involvement in various physiological processes and potential implications in pathological conditions. Initially identified in the context of the immune system, GPR83 is expressed in various tissues, including the central nervous system, and has been linked to hormonal regulation, stress responses, and metabolic control. Its involvement in immune cell function suggests a role in inflammatory diseases and autoimmune conditions. Recent studies have indicated that GPR83 may play a crucial role in modulating the function of immune cells, particularly T cells and macrophages. Given its significance, researchers have focused on producing recombinant GPR83 protein to elucidate its structure and function further. Recombinant protein studies enable the characterization of GPR83's ligand-binding properties, signaling pathways, and interactions with other cellular components. Understanding the molecular mechanisms of GPR83 could open new avenues for therapeutic interventions, especially in metabolic disorders and immune-related diseases. Thus, the exploration of GPR83 as a potential drug target and the creation of a recombinant protein model pave the way for a deeper understanding of its biological roles and therapeutic prospects.
