Analytical Data
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基因名
SFTPA1
- Application
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别名
SFTPA1；COLEC4；PSAP；SFTP1；Pulmonary surfactant-associated Protein A1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IWL2
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表达区间
21-248aa
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氨基酸序列
EVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF
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分子量
31.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SFTPA1, or Surfactant Protein A1, is a crucial protein involved in the lung’s surfactant system, playing a significant role in surfactant homeostasis, host defense, and the modulation of immune responses in the respiratory system. A deficiency or dysfunction of SFTPA1 is associated with various pulmonary disorders, including interstitial lung disease, pulmonary surfactant dysfunction, and some forms of pneumonia. The study of recombinant SFTPA1 protein is essential for understanding its molecular mechanisms, interactions with pathogens, and potential therapeutic applications. Research has increasingly focused on the structural and functional characteristics of SFTPA1 to elucidate its role in lung biology and pathology. Moreover, recombinant SFTPA1 can serve as a valuable tool in drug development and predictive models for lung diseases, with the objective of creating targeted therapies to ameliorate respiratory conditions. This protein's unique properties allow it to interact with a wide range of molecules, making it a focal point in studies aiming to bridge the gap between basic research and clinical applications in pulmonary health. By generating recombinant forms of SFTPA1, researchers aim to explore its potential in enhancing surfactant function, improving lung immunity, and developing novel treatments for respiratory ailments.
