Analytical Data
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基因名
TECK
- Application
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别名
TECK;SCYA25;TECK;C-C motif chemokine 25
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15444
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表达区间
24-150aa
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氨基酸序列
M+QGVFEDCCL AYHYPIGWAV LRRAWTYRIQ EVSGSCNLPA AIFYLPKRHR KVCGNPKSRE VQRAMKLLDA RNKVFAKLHH NTQTFQAGPH AVKKLSSGNS KLSSSKFSNP ISSSKRNVSL LISANSGL
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分子量
14.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TECK, or T-cell deubiquitinating enzyme, is a significant protein involved in the regulation of T-cell responses and immune system functions. Research on TECK has gained traction due to its crucial role in modulating immune signaling pathways, particularly those related to T-cell activation and survival. Its function is primarily linked to the removal of ubiquitin moieties from proteins, which can either stabilize or target them for degradation, thus influencing the overall immune response. Understanding the structural and functional aspects of TECK is vital for developing therapeutic strategies for immune-related diseases, such as autoimmune disorders and cancers, where T-cell regulation can be impaired. Recent studies focus on elucidating the biochemical mechanisms by which TECK operates, including its interaction with other regulatory proteins and its influence on signaling cascades. This research not only sheds light on the fundamental biology of T-cell regulation but also opens avenues for potential interventions that could enhance immune response or reestablish normal immune function in pathological conditions. By exploring the molecular dynamics of TECK, scientists aim to identify novel drug targets and biomarkers that could lead to improved treatments for diseases characterized by dysfunctional T-cell activity.












