Analytical Data
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基因名
NDRG2
- Application
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别名
NDRG2;KIAA1248;SYLD;Protein NDRG2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UN36
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表达区间
1-357aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMAELQE VQITEEKPLL PGQTPEAAKT HSVETPYGSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VGDQAPHEDA VVECNSKLDP TQTSFLKMAD SGGQPQLTQP GKLTEAFKYF LQGMGYMASS CMTRLSRSRT ASLTSAASVD GNRSRSRTLS QSSESGTLSS GPPGHTMEVS C
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分子量
42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NDRG2 (N-myc downstream-regulated gene 2) is a member of the NDRG family of proteins, which are implicated in various cellular processes, including differentiation, growth inhibition, and stress responses. Altered expression of NDRG2 has been associated with several pathological conditions, including cancer, where it can function as a tumor suppressor, and neurodegenerative diseases, indicating its role in cellular homeostasis and survival. Studies have shown that NDRG2 can influence cancer cell proliferation, migration, and apoptosis, making it a potential biomarker for prognosis and a target for therapeutic intervention. Researchers have focused on recombinant NDRG2 protein to elucidate its function and mechanism of action at the molecular level. By producing and characterizing this protein, scientists aim to explore its structural properties, interactions with other proteins, and its influence on signaling pathways. Understanding the functional roles of NDRG2 through recombinant protein studies could provide insights into its involvement in disease pathology and reveal new avenues for targeted therapies, particularly in cancers where NDRG2 expression is disrupted. Overall, the investigation of NDRG2 as a recombinant protein represents a significant step toward unraveling its biological significance and therapeutic potential in various diseases.
