Analytical Data
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基因名
KRT24
- Application
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别名
KRT24；KA24；Keratin. type I cytoskeletal 24
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q2M2I5
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表达区间
1-525aa
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氨基酸序列
MSCSSRASSSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISEVKVK
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分子量
57.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT24, or Keratin 24, is a member of the keratin family of proteins, primarily expressed in the skin, hair, and nails. Research into KRT24 has gained traction due to its potential role in epidermal differentiation and the formation of the skin barrier, crucial for protecting against environmental factors. Keratins, including KRT24, are key structural components of epithelial tissues and are implicated in various skin disorders and diseases. Previous studies have indicated that the expression of KRT24 may be altered in conditions such as psoriasis, eczema, and other keratinization disorders, highlighting its significance in dermatological health. Additionally, KRT24's involvement in cell proliferation and migration suggests its potential utility in wound healing and tissue regeneration. The recombinant expression of KRT24 allows for the detailed investigation of its biochemical properties and functional roles in cellular contexts. By generating KRT24 protein through recombinant DNA technology, researchers can explore its interactions with other proteins, understand its mechanistic pathways, and assess its therapeutic potential. This research lays the groundwork for developing targeted treatments for skin-related conditions and enhancing regenerative medicine strategies. Overall, KRT24 represents an exciting area of study within the broader field of keratin biology, with implications for both basic science and clinical applications in dermatology.
