Analytical Data
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基因名
TEC
- Application
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别名
TEC;PSCTK4;Tyrosine-Protein kinase Tec
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P42680
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表达区间
1-631aa
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氨基酸序列
MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGRAEKKYRKGFIDVSKIKCVEIVKNDDGVIPCQNKYPFQVVHDANTLYIFAPSPQSRDLWVKKLKEEIKNNNNIMIKYHPKFWTDGSYQCCRQTEKLAPGCEKYNLFESSIRKALPPAPETKKRRPPPPIPLEEEDNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSYEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEETFGR
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分子量
103 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TEC (T Cell-Receptor-Associated Protein) recombinant proteins have emerged as a critical area of study in immunology and biotechnology due to their vital roles in T cell signaling and immune response. TEC family proteins, including TEC, BTK, and ITK, are non-receptor tyrosine kinases that play essential roles in various cellular processes such as proliferation, differentiation, and survival of immune cells. The understanding of how these proteins function at a molecular level is crucial for developing targeted therapies for immune-related diseases, including autoimmune disorders and cancers. With advancements in recombinant DNA technology, researchers have successfully produced TEC recombinant proteins, facilitating in-depth studies of their structure, function, and interaction with other cellular components. These studies not only enhance our understanding of T cell biology but also pave the way for novel therapeutic strategies, including monoclonal antibodies and small-molecule inhibitors that can modulate T cell activity in disease contexts. The potential applications of TEC recombinant proteins extend beyond immunotherapy, as they also hold promise in vaccine development and personalized medicine approaches. As a result, ongoing research in this field is aimed at elucidating the precise mechanisms through which TEC family proteins influence immune system dynamics, hopefully leading to breakthroughs in treating complex diseases influenced by immune dysfunction.












