Analytical Data
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Gene name
GALR4
- Application
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Alternative Names
GALR4；GALR4；GALRL；PGR7；G-Protein coupled receptor 151
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TDV0
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Expression Region
1-419aa
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AA Sequence
MLAAAFADSNSSSMNVSFAHLHFAGGYLPSDSQDWRTIIPALLVAVCLVGFVGNLCVIGILLHNAWKGKPSMIHSLILNLSLADLSLLLFSAPIRATAYSKSVWDLGWFVCKSSDWFIHTCMAAKSLTIVVVAKVCFMYASDPAKQVSIHNYTIWSVLVAIWTVASLLPLPEWFFSTIRHHEGVEMCLVDVPAVAEEFMSMFGKLYPLLAFGLPLFFASFYFWRAYDQCKKRGTKTQNLRNQIRSKQVTVMLLSIAIISALLWLPEWVAWLWVWHLKAAGPAPPQGFIALSQVLMFSISSANPLIFLVMSEEFREGLKGVWKWMITKKPPTVSESQETPAGNSEGLPDKVPSPESPASIPEKEKPSSPSSGKGKTEKAEIPILPDVEQFWHERDTVPSVQDNDPIPWEHEDQETGEGVK
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Molecular Weight
46.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GALR4, a member of the galanin receptor family, plays a crucial role in various physiological processes, including regulation of mood, pain perception, and neuroendocrine functions. Research interest in GALR4 has grown due to its potential implications in various neuropsychiatric disorders, metabolic syndromes, and cancer. The galanin system, particularly through its interactions with GALR4, has been implicated in the modulation of neurotransmitter release, neuronal survival, and inflammatory responses. Advances in biotechnology have enabled the production of recombinant GALR4 proteins, which are essential for investigating the receptor's structure, function, and interactions with ligands. By using techniques such as genetic engineering and expression in suitable cell systems, researchers can obtain large quantities of functional GALR4 for use in biochemical assays and drug discovery. This research is critical for elucidating the precise mechanisms by which GALR4 influences physiological and pathological processes, which could lead to the development of targeted therapeutics for conditions linked to galanin dysregulation.
