Analytical Data
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基因名
Prolactin
- Application
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别名
PRLH;PRH;Prolactin-releasing peptide
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P16471
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表达区间
25-234aa
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氨基酸序列
QLPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPSDFTMND
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分子量
27.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Prolactin is a peptide hormone primarily produced by the pituitary gland, playing a crucial role in various physiological processes, including lactation, reproduction, and immune regulation. Recent advancements in biotechnology have enabled the production of recombinant prolactin, allowing researchers to study its structure-function relationships more thoroughly. The recombinant form offers several advantages, such as higher purity, consistent supply, and the ability to manipulate its genetic structure for functional assays or therapeutic applications. Investigations into recombinant prolactin have demonstrated its potential in addressing reproductive disorders, enhancing lactation in dairy animals, and serving as a target for novel therapeutic interventions in diseases associated with prolactin dysregulation, such as prolactinomas or certain infertility issues. Furthermore, understanding the molecular mechanisms by which prolactin exerts its effects, through specific receptors and signaling pathways, remains a significant focus of research. These insights not only contribute to the fundamental understanding of hormonal regulation but also pave the way for innovative strategies in clinical settings, highlighting the importance of recombinant prolactin in both scientific research and practical applications.
