Analytical Data
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Gene name
ACAD9
- Application
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Alternative Names
ACAD9Complex I assembly factor ACAD9; mitochondrial; Acyl-CoA dehydrogenase family member 9
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal.
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H845
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Expression Region
1- 621a.a
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AA Sequence
MSGCGLFLRTTAAARACRGLVVSTANRRLLRTSPPVRAFAKELFLGKIKKKEVFPFPEVSQDELNEINQFLGPVEKFFTEEVDSRKIDQEGKIPDETLEKLKSLGLFGLQVPEEYGGLGFSNTMYSRLGEIISMDGSITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGEHIAAFCLTEPASGSDAASIRSRATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVDSDGSVKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILGEVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLSEFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIALTGLQHAGRILTTRIHELKQAKVSTVMDTVGRRLRDSLGRTVDLGLTGNHGVVHPSLADSANKFEENTYCFGRTVETLLLRFGKTIMEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANTFCVEAYLQNLFSLSQLDKYAPENLDEQIKKVSQQILEKRAYICAHPLDRTC
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Molecular Weight
95.2 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACAD9, also known as acyl-CoA dehydrogenase family member 9, plays a crucial role in the mitochondrial fatty acid oxidation pathway, particularly in the metabolism of medium-chain fatty acids. Research has highlighted its importance in maintaining energy homeostasis and its involvement in various metabolic disorders. Mutations or deficiencies in ACAD9 are linked to complex genetic conditions, including severe infantile metabolic crises, suggesting its vital function in cellular energy production. The study of ACAD9 recombinant proteins has gained momentum as scientists strive to understand its structure-function relationship, regulation, and interactions with other metabolic enzymes. Additionally, investigating ACAD9 could reveal insights into potential therapeutic strategies for related metabolic diseases. Due to the limited availability of natural ACAD9, producing recombinant forms enables the exploration of its biochemical properties and interactions, facilitating drug design and the development of targeted therapies for mitochondrial dysfunction. Overall, ACAD9 remains a significant focus within metabolic research, aiming to unravel the complexities of fatty acid metabolism and its implications for human health.
