Analytical Data
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基因名
SLC7A14
- Application
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别名
SLC7A14; KIAA1613; Probable cationic amino acid transporter; Solute carrier family 7 member 14
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TBB6
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表达区间
1-737 aa
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氨基酸序列
MLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGDNEMLIGKSDKSTYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMDRPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQEDWGGPTEDKGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE
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分子量
106.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC7A14, a member of the solute carrier family, encodes a protein that functions as an amino acid transporter and is predominantly expressed in various tissues, including the brain and kidneys. Its precise physiological role remains largely unclear, but emerging research suggests that SLC7A14 is involved in diverse processes such as nutrient transport, ion homeostasis, and possibly the modulation of cell signaling pathways. Given its potential implications in human health and disease, including metabolic disorders and neurological conditions, the recombinant expression of SLC7A14 in heterologous systems offers a valuable avenue for in-depth functional studies. By producing the protein in sufficient quantities, researchers can investigate its structural properties, substrate specificity, and transport mechanisms. Additionally, understanding the regulation of SLC7A14 expression and activity could reveal insights into its involvement in pathological states. Recent advancements in protein purification techniques and functional assays have facilitated the exploration of SLC7A14's interactions with ligands and other cellular constituents, paving the way for future therapeutic interventions targeting this transporter. As such, recombinant SLC7A14 serves as a critical tool for unraveling its complex biological roles and understanding its potential as a biomarker or therapeutic target in related diseases. This research area remains vibrant, promising to yield important discoveries that could impact various fields, including pharmacology, biochemistry, and molecular biology.
