Analytical Data
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基因名
SPANXA1
- Application
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别名
SPANXA1; SPANXA;; SPANXA2; Sperm protein associated with the nucleus on the X chromosome A; Cancer/testis antigen 11.1; CT11.1; Nuclear-associated protein SPAN-Xa; SPAN-X; SPANX-A; SPANX family member A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NS26
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表达区间
1-97 aa
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氨基酸序列
MDKQSSAGGV KRSVPCDSNE ANEMMPETPT GDSDPQPAPK KMKTSESSTI LVVRYRRNFK RTSPEELLND HARENRINPL QMEEEEFMEI MVEIPAK
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分子量
11.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SPANXA1 (spermatogenic and testis-specific protein) is a member of the cancer/testis (CT) antigen family, which is predominantly expressed in germ cells of the testis and in various malignant tumors, but not in normal somatic tissues. This unique expression pattern makes SPANXA1 an attractive target for immunotherapy, particularly in cancer treatment, as it can elicit immune responses while minimizing damage to normal cells. Research has indicated that SPANXA1 may play a critical role in tumorigenesis and potentially contribute to the survival and proliferation of cancer cells. Understanding the functional characteristics of SPANXA1 and developing recombinant SPANXA1 proteins can provide valuable insights into its biological role and enhance therapeutic strategies. The generation of SPANXA1 recombinant proteins allows for the examination of their antigenic properties and interactions with the immune system, paving the way for the development of targeted cancer vaccines. As a result, SPANXA1 is gaining attention in the fields of oncology and immunology, as researchers explore its potential implications in cancer diagnosis, prognosis, and treatment to improve patient outcomes.












