Analytical Data
-
基因名
Acss2
- Application
-
别名
Acss2；ACAS2；Acetyl-coenzyme A synthetase. cytoplasmic
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NR19
-
表达区间
1-701aa
-
氨基酸序列
MGLPEERVRS GSGSRGQEEA GAGGRARSWS PPPEVSRSAH VPSLQRYREL HRRSVEEPRE FWGDIAKEFY WKTPCPGPFL RYNFDVTKGK IFIEWMKGAT TNICYNVLDR NVHEKKLGDK VAFYWEGNEP GETTQITYHQ LLVQVCQFSN VLRKQGIQKG DRVAIYMPMI PELVVAMLAC ARIGALHSIV FAGFSSESLC ERILDSSCSL LITTDAFYRG EKLVNLKELA DEALQKCQEK GFPVRCCIVV KHLGRAELGM GDSTSQSPPI KRSCPDVQIS WNQGIDLWWH ELMQEAGDEC EPEWCDAEDP LFILYTSGST GKPKGVVHTV GGYMLYVATT FKYVFDFHAE DVFWCTADIG WITGHSYVTY GPLANGATSV LFEGIPTYPD VNRLWSIVDK YKVTKFYTAP TAIRLLMKFG DEPVTKHSRA SLQVLGTVGE PINPEAWLWY HRVVGAQRCP IVDTFWQTET GGHMLTPLPG ATPMKPGSAT FPFFGVAPAI LNESGEELEG EAEGYLVFKQ PWPGIMRTVY GNHERFETTY FKKFPGYYVT GDGCQRDQDG YYWITGRIDD MLNVSGHLLS TAEVESALVE HEAVAEAAVV GHPHPVKGEC LYCFVTLCDG HTFSPKLTEE LKKQIREKIG PIATPDYIQN APGLPKTRSG KIMRRVLRKI AQNDHDLGDM STVADPSVIS HLFSHRCLTI Q
-
分子量
78.5 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACSS2 (Acetyl-CoA synthetase 2) is a critical enzyme involved in the metabolism of acetate, converting acetate to acetyl-CoA, a key metabolic intermediate that plays a vital role in various biochemical pathways, including energy production, lipid synthesis, and the citric acid cycle. Its significance has become increasingly evident with the growing understanding of metabolic dysregulation in diseases such as cancer, obesity, and neurodegenerative disorders. Research has shown that ACSS2 is upregulated in certain cancer types, suggesting a pivotal role in supporting tumor growth by facilitating anabolic processes and enabling cancer cells to thrive in low-nutrient environments. The study of ACSS2 recombinant protein is essential for elucidating its functional properties, structural characteristics, and regulatory mechanisms. By producing and characterizing ACSS2 in a laboratory setting, researchers aim to investigate its enzymatic activity, substrate specificity, and interaction with other metabolic pathways. Furthermore, understanding the role of ACSS2 in energy homeostasis and its response to physiological and pathological stimuli could lead to novel therapeutic strategies aimed at targeting metabolic pathways in various diseases. As such, the recombinant expression of ACSS2 provides a crucial tool for advancing our knowledge of its biological functions and potential as a drug target in metabolic diseases and cancers.
