Analytical Data
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基因名
SPIB
- Application
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别名
SPI B; Spi B transcription factor; Spib; SPIB_HUMAN; Transcription factor Spi-B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q01892
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表达区间
1-262aa
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氨基酸序列
MLALEAAQLD GPHFSCLYPD GVFYDLDSCK HSSYPDSEGA PDSLWDWTVA PPVPATPYEA FDP aaFSH PQAAQLCYEP PTYSPAGNLE LAPSLEAPGP GLPAYPTENF ASQTLVPPAY APYPSPVLSE EEDLPLDSPA LEVSDSESDE ALVAGPEGKG SEAGTRKKLR LYQFLLGLLT RGDMRECVWW VEPGAGVFQF SSKHKELLAR RWGQQKGNRK RMTYQKLARA LRNYAKTGEI RKVKRKLTYQ FDSALLPAVR RA
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分子量
28.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of SPIB (Spi-1/PU.1 Interacting Protein) recombinant proteins has gained significant traction in recent years due to its pivotal role in immunology and hematopoiesis. SPIB is a transcription factor crucial for the development and function of various immune cells, including B cells, T cells, and dendritic cells. Researchers have identified that SPIB interacts with other proteins and transcription factors, influencing gene expression patterns that are essential for immune response and homeostasis. Understanding the molecular mechanisms underlying SPIB's interactions is vital for elucidating its role in immune system diseases and disorders, such as autoimmune diseases and cancers. The development of recombinant SPIB proteins allows for precise studies into their structure, function, and interactions at the molecular level. These proteins can be expressed in various systems, offering a platform for functional assays and potential therapeutic applications. By further characterizing SPIB through recombinant technologies, researchers aim to uncover new avenues for intervention in immune-related pathologies, making this research area a promising frontier in both basic and translational science. Through this work, scientists hope to develop targeted strategies that can modulate SPIB activity, enhancing immune responses or curbing pathological conditions, ultimately contributing to advances in immunotherapy and personalized medicine.
