Analytical Data
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基因名
TFDP3
- Application
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别名
Cancer/testis antigen 30; CT30; DP4; E2F like Protein; E2F-like; HCA661; Hepatocellular carcinoma-associated antigen 661; TFDP3; TFDP3_HUMAN; Transcription factor Dp family member 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5H9I0
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表达区间
1-405 aa
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氨基酸序列
MAKYVSLTEA NEELKVLMDE NQTSRPVAVH TSTVNPLGKQ LLPKTFGQSS VNIDQQVVIG MPQRPAASNI PVVGSPNPPS THFASQNQHS YSSPPWAGQH NRKGEKNGMG LCRLSMKVWE TVQRKGTTSC QEVVGELVAK FRAASNHASP NESAYDVKNI KRRTYDALNV LMAMNIISRE KKKIKWIGLT TNSAQNCQNL RVERQKRLER IKQKQSELQQ LILQQIAFKN LVLRNQYVEE QVSQRPLPNS VIHVPFIIIS SSKKTVINCS ISDDKSEYLF KFNSSFEIHD DTEVLMWMGM TFGLESGSCS AEDLKMARNL VPKALEPYVT EMAQGTFGGV FTTAGSRSNG TWLSASDLTN IAIGMLATSS GGSQYSGSRV ETPAVEEEEE EDNNDDDLSE NDEDD
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分子量
44.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TFDP3 (Transcription Factor Dp-3) is a member of the Dp family of transcription factors, which play a critical role in regulating the cell cycle and gene expression by interacting with E2F transcription factors. The study of TFDP3 has gained attention due to its potential involvement in cancer progression and development, particularly in the context of cell proliferation and differentiation. Research has shown that TFDP3 can modulate E2F activity, influencing the expression of genes responsible for cell cycle regulation. Additionally, aberrant regulation of TFDP3 has been implicated in various malignancies, making it a target for therapeutic intervention. The understanding of TFDP3 functions at the molecular level is essential for unraveling its role in oncogenesis and for developing innovative strategies to combat cancer. Recent studies have also focused on the structure-function relationships of TFDP3 and its interactions with other proteins in the signaling pathways that govern cell growth and survival. As such, the recombinant expression of TFDP3 can provide valuable insights into its biochemical properties and facilitate high-throughput screening for potential inhibitors or modulators of its activity, paving the way for novel cancer treatments. Together, these studies underpin the importance of TFDP3 as a vital component in the intricate network of cellular regulation and highlight the need for further research to elucidate its precise mechanisms of action.
