Analytical Data
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Gene name
PSMB10
- Application
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Alternative Names
Low molecular mass protein 10 Macropain subunit MECl-1 Multicatalytic endopeptidase complex subunit MECl-1 Proteasome MECl-1 Proteasome subunit beta-2i
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P40306
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Expression Region
1-273aa
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Molecular Weight
51.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PSMB10, also known as proteasome subunit beta type-10, is a critical component of the 26S proteasome, which plays a pivotal role in protein degradation and cellular homeostasis. Research on PSMB10 has garnered significant interest due to its involvement in various cellular processes, including antigen processing, regulation of gene expression, and modulation of cell cycle events. Additionally, PSMB10 is implicated in several diseases, particularly cancer and viral infections, where its expression levels can influence the survival and proliferation of malignant cells. The study of recombinant PSMB10 proteins aims to elucidate its structural and functional properties, allowing for a better understanding of its role in the proteasome complex and its interactions with other cellular components. Moreover, recombinant PSMB10 can serve as a valuable tool in therapeutic applications, such as developing proteasome inhibitors that target specific cancer cells or enhancing the immune response against viral pathogens. By producing and characterizing this protein, researchers are not only contributing to the fundamental understanding of proteasomal functions but also paving the way for potential clinical interventions through targeted therapies.
