Analytical Data
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基因名
AIP
- Application
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别名
AIP;XAP2;AH receptor-interacting Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00170
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表达区间
1-330aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHPVWETIVCTMREGEIAQFLCDIKHVVLYPL VAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIF HMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAA KYYDAIACLKNLQMKEQPGSPEWIQLDKQITPLLLNYCQCKLVVEEYYEV MADIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVL DDSRARGKPMELIIGKKFKLLDHCSSILNKYDDNVKAYFKRGKAHAAVWN AQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH
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分子量
40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AIP (Apoptosis-Inhibiting Protein) is a key player in the regulation of apoptotic processes and has garnered significant interest in the field of molecular and cellular biology. The study of AIP and its recombinant protein forms is rooted in the understanding that apoptosis, or programmed cell death, is crucial for maintaining cellular homeostasis and proper organism development. Dysregulation of apoptotic pathways has been implicated in a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune conditions, making AIP a prominent target for therapeutic interventions. Researchers have focused on isolating and characterizing the recombinant forms of AIP to explore their structural and functional properties. By employing techniques such as recombinant DNA technology, scientists can produce AIP in host systems like bacteria or yeast, facilitating large-scale production and detailed biochemical studies. Furthermore, understanding AIP’s interactions with other apoptotic regulators and signaling pathways can provide insights into its role in disease mechanisms and therapeutic strategies. The exploration of AIP recombinant proteins also opens pathways for the development of novel drugs or biological agents that can modulate apoptosis, offering potential avenues for treatment in various pathologies where apoptotic regulation is compromised. As research progresses, the manipulation of AIP through recombinant technology continues to highlight its importance in both fundamental biology and clinical applications, underscoring the necessity of understanding protein behavior in therapeutic contexts.












