Analytical Data
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基因名
GPR132
- Application
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别名
(G2 accumulation protein)
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种属
Human
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表达系统
E. coli
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标签
N- His-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UNW8
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表达区间
311-380aa
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分子量
39.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPR132, also known as G-protein coupled receptor 132 or GPRC5A, is a member of the adhesion family of GPCRs and has been implicated in various physiological and pathological processes. Initially identified in the context of immune responses and inflammation, GPR132 plays a crucial role in modulating cellular activities such as proliferation, migration, and differentiation. Recent research has suggested its involvement in cancer progression, particularly in regulating tumor microenvironments and mediating cancer cell metabolism. Given its potential as a therapeutic target, understanding the structure and function of GPR132 is essential. The recombinant production of GPR132 can facilitate detailed studies on its ligand binding properties, signal transduction mechanisms, and interaction with other cellular proteins. This research is vital for elucidating the receptor's role in disease and could lead to novel treatment strategies targeting GPR132 in various conditions, including cancer and other inflammatory diseases. Analyzing GPR132 through recombinant proteins allows researchers to obtain purified samples for in vitro assays, which are critical for drug discovery efforts aimed at modulating its activity for therapeutic benefits.
