Analytical Data
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基因名
TMOD4
- Application
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别名
Skeletal muscle tropomodulin
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NZQ9
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表达区间
1-345aa
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分子量
66.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMOD4, or tropomodulin 4, is a member of the tropomodulin family of proteins known for their role in actin filament regulation and stabilization. As a key component in the tropomyosin-actin complex, TMOD4 is primarily expressed in striated muscle tissues and plays a crucial role in maintaining the integrity and proper functioning of the sarcomere, the basic contractile unit of muscle fibers. Research into TMOD4 has gained momentum due to its implications in various physiological processes and its potential association with muscle-related diseases and disorders. Understanding the structure and function of TMOD4 is vital for elucidating its mechanisms in muscle physiology, including muscle contraction, signaling pathways, and interaction with other cytoskeletal proteins. Furthermore, abnormalities in TMOD4 expression or function have been linked to muscle weakness and cardiomyopathies, making it a target of interest for therapeutic interventions. Recent studies have employed techniques like recombinant protein expression and purification to explore TMOD4's biochemical properties, interactions, and functional roles in muscle tissue. This research is crucial not only for basic science but also for the development of potential strategies to combat muscle diseases, highlighting the significance of TMOD4 in the broader context of muscle biology and pathology.
