Analytical Data
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Gene name
ERLIN2
- Application
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Alternative Names
ERLIN2；C8orf2；SPFH2;Erlin-2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O94905
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Expression Region
25-339aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSKIEEGHIGVYYRGGALLTSTSGPGFHL MLPFITSYKSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVY DIVKNYTADYDKALIFNKIHHELNQFCSVHTLQEVYIELFDQIDENLKLA LQQDLTSMAPGLVIQAVRVTKPNIPEAIRRNYELMESEKTKLLIAAQKQK VVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFL AREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDI PNMFMDSAGSVSKQFEGLADKLSFGLEDEPLETATKEN
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Molecular Weight
38 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ERLIN2, a member of the ERLIN family, has garnered significant attention in recent years due to its vital role in various cellular processes. Initially identified in the context of endoplasmic reticulum (ER) function, ERLIN2 is believed to be involved in the regulation of quality control mechanisms within the ER, particularly in the degradation of misfolded proteins through the ER-associated degradation (ERAD) pathway. Research has suggested that ERLIN2 interacts with key components of the ubiquitin-proteasome system, which is crucial for maintaining cellular homeostasis. Furthermore, studies have indicated that ERLIN2 might play a role in modulating immune responses and cellular apoptosis, linking it to potential implications in diseases such as cancer and autoimmune disorders. The exploration of ERLIN2 as a recombinant protein offers promising avenues for understanding its structural characteristics and functional dynamics, which could lead to novel therapeutic strategies. Given its pivotal role in maintaining ER integrity and protein homeostasis, ERLIN2 represents a fascinating target for further investigation into its mechanistic pathways and biological significance.
