Analytical Data
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Gene name
GOAT
- Application
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Alternative Names
GOAT；GOAT；OACT4；Ghrelin O-acyltransferase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96T53
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Expression Region
1-435aa
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AA Sequence
MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN
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Molecular Weight
49.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of GOAT (ghrelin O-acyltransferase) recombinant proteins has gained significant attention in the field of metabolic research and endocrinology. GOAT is an enzyme responsible for the acylation of ghrelin, a peptide hormone that plays a crucial role in regulating appetite and energy balance. The acylation process enhances ghrelin's biological activity, thus influencing metabolic pathways related to weight regulation, hunger signaling, and growth hormone release. Research into GOAT recombinant proteins aims to understand its structure-function relationships, regulatory mechanisms, and potential therapeutic applications. Given the rising prevalence of obesity and related metabolic disorders, insights gained from GOAT research could lead to innovative interventions targeting appetite control and metabolic health. Furthermore, recombinant technologies facilitate the production of GOAT variants with altered enzymatic properties, enabling detailed studies of its role in metabolic processes and the potential development of GOAT inhibitors or enhancers as novel therapies for obesity and other endocrine disorders. Thus, the exploration of GOAT recombinant proteins represents a promising avenue for advancing our understanding of metabolic regulation and addressing pressing public health challenges.
