Analytical Data
-
基因名
GTF2IRD2
- Application
-
别名
GTF2IRD2; GTF2IRD2A; General transcription factor II-I repeat domain-containing protein 2A; GTF2I repeat domain-containing protein 2A; Transcription factor GTF2IRD2-alpha
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q86UP8
-
表达区间
1-498aa
-
氨基酸序列
MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNGLLEAGAGGLLEAGSLRPAWATWQDPISTKNLKISWKQWLTPVAPATWQAEAGGSLELRSLRQQRTIIAILHSSLGDRTRPCL
-
分子量
80.8 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GTF2IRD2, a gene located on chromosome 7, encodes a protein that is part of the GTF2I family, which is involved in various cellular processes including transcription regulation and developmental pathways. Research on GTF2IRD2 has gained significance due to its association with Williams syndrome, a genetic condition characterized by cardiovascular disease, developmental delays, and distinctive facial features. Studies have shown that GTF2IRD2 plays a crucial role in neuronal development and function, which suggests its potential impact on cognitive abilities. Furthermore, GTF2IRD2 has been linked to the modulation of the expression of other genes involved in neural processes. Recombinant GTF2IRD2 protein studies aim to elucidate its structural and functional properties, enabling researchers to better understand its role in both normal and pathological states. The production of this recombinant protein facilitates biochemical assays and functional studies, offering insights into how mutations or dysregulation of GTF2IRD2 may contribute to the phenotypic manifestations of related disorders. Overall, studying GTF2IRD2 and its recombinant protein form holds promise for advancing our understanding of its biological functions and implications in human health, particularly in neurodevelopmental and genetic conditions.
