Analytical Data
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Gene name
KLF9
- Application
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Alternative Names
Basic transcription element binding protein 1; Basic transcription element-binding protein 1; BTE binding protein 1; BTE-binding protein 1; BTEB 1; BTEB; BTEB1; GC box binding protein 1; GC-box-binding protein 1; KLF 9; KLF9; KLF9_HUMAN
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13886
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Expression Region
1-244aa
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AA Sequence
MSAAAYMDFVAAQCLVSISNRAAVPEHGVAPDAERLRLPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDMGSDSDVTTESGSSPSHSPEERQDPGSAPSPLSLLHPGVAAKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKRSKKALANAL
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Molecular Weight
26.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KLF9, or Krüppel-like factor 9, is a member of the Krüppel-like factor family of transcription factors, playing a crucial role in various biological processes, including cell differentiation, proliferation, and apoptosis. Research has demonstrated that KLF9 is implicated in essential physiological functions, such as regulating gene expression in embryonic development and maintaining stem cell pluripotency. Dysregulation of KLF9 has been associated with several diseases, including cancer, where it can act as a tumor suppressor or an oncogene depending on the context. The investigation of KLF9 recombinant protein has gained traction as it allows for the detailed study of its structure-function relationships and interactions with target genes. Understanding KLF9's function at the protein level also provides insights into its potential therapeutic applications, particularly in regenerative medicine and cancer therapy. By creating a fully characterized recombinant KLF9 protein, researchers can explore its biochemical properties, post-translational modifications, and interactions with other proteins, paving the way for developing novel strategies to manipulate its activity in various biological contexts. This research not only enhances our comprehension of KLF9's role in health and disease but also holds promise for advancing targeted therapies that exploit its regulatory mechanisms.
