Analytical Data
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Gene name
RD3
- Application
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Alternative Names
RD3；C1orf36；Protein RD3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7Z3Z2
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Expression Region
1-195aa
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AA Sequence
MSLISWLRWNEAPSRLSTRSPAEMVLETLMMELTGQMREAERQQRERSNAVRKVCTGVDYSWLASTPRSTYDLSPIERLQLEDVCVKIHPSYCGPAILRFRQLLAEQEPEVQEVSQLFRSVLQEVLERMKQEEEAHKLTRQWSLRPRGSLATFKTRARISPFASDIRTISEDVERDTPPPLRSWSMPEFRAPKAD
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Molecular Weight
30.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of RD3 recombinant protein has garnered significant interest due to its potential role in understanding and addressing various retinal diseases, particularly those linked to inherited retinal dystrophies. RD3, or retinitis pigmentosa 13 protein, is associated with rod and cone photoreceptor function and is crucial for photoreceptor cell integrity. Mutations in the RD3 gene have been implicated in severe forms of blindness, highlighting its importance in retinal health. Recombinant protein studies help elucidate the biochemical pathways involved in RD3 functioning and its interaction with other proteins within the retinal environment. By producing RD3 in a laboratory setting, researchers can investigate its structural properties and cellular mechanisms, paving the way for gene therapy approaches and potential treatments for patients suffering from conditions related to RD3 mutations. Furthermore, understanding the role of RD3 in phototransduction and photoreceptor maintenance could unlock new strategies for combating retinal degenerative diseases, thus contributing to the broader field of regenerative medicine and vision restoration therapies. Overall, RD3 recombinant protein research is crucial for developing targeted interventions, enhancing our understanding of retinal biology, and ultimately improving outcomes for affected individuals.
