Analytical Data
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Gene name
NARG2
- Application
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Alternative Names
ICE2; BRCC1; NARG2; UNQ3101/PRO10100; Little elongation complex subunit 2; Interactor of little elongator complex ELL subunit 2; NMDA receptor-regulated protein 2
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q659A1
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Expression Region
1-332 aa
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AA Sequence
MQDELLKPISRKVPELPLMNLENSKQPSVSEQLSGPSDSSSWPKSGWPSAFQKPKGRLPYELQDYVEDTSEYLAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISNLFNILQHILKKLSSLQEGSYLLSHAAEDSSLLIYKASDGKVTRTAYNLYKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLDTTTQQKIGGTRMPTRSHRNPVSMETKSSCLPAQQVETEGVAPHKRKIT
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Molecular Weight
64 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NARG2, or NLR family CARD domain containing 2, is a member of the NLR (nucleotide-binding oligomerization domain-like receptor) family, which plays a critical role in the immune system by serving as intracellular sensors for pathogen-associated molecular patterns and danger signals. The study of NARG2 recombinant proteins has gained traction due to its potential involvement in various inflammatory diseases and autoimmune disorders. Researchers are particularly interested in understanding how NARG2 interacts with other proteins in the immune signaling pathways and its role in modulating inflammatory responses. Given its structural characteristics, which include a nucleotide-binding domain and CARD (caspase activation and recruitment domain), NARG2 may influence the activation of caspases and other downstream signaling molecules. Investigating the recombinant form of NARG2 allows scientists to dissect its functional properties, evaluate its potential as a therapeutic target, and develop novel strategies for intervention in diseases marked by dysregulated immune responses. The growing body of research surrounding NARG2 highlights its significance in unraveling the complexities of innate immunity and offers promising avenues for therapeutic development in treating diseases characterized by aberrant inflammation.
