Analytical Data
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Gene name
TAF13
- Application
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Alternative Names
TAF13；TAF2K；TAFII18；Transcription initiation factor TFIID subunit 13
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15543
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Expression Region
1-124aa
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AA Sequence
MADEEEDPTF EEENEEIGGG AEGGQGKRKR LFSKELRCMM YGFGDDQNPY TESVDILEDL VIEFITEMTH KAMSIGRQGR VQVEDIVFLI RKDPRKFARV KDLLTMNEEL KRARKAFDEA NYGS
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TAF13, a crucial component of the Transcription Factor IID (TFIID) complex, plays a significant role in the regulation of gene expression by bridging the interactions between general transcription factors and RNA polymerase II. Recent studies have highlighted the importance of TAF13 in various cellular processes, including cell proliferation, differentiation, and response to stress, indicating its fundamental role in maintaining cellular homeostasis. Additionally, mutations or dysregulation of TAF13 have been implicated in several diseases, including cancers, which further underscores its potential as a therapeutic target. The recombinant expression of TAF13 has facilitated detailed investigations into its functional mechanisms, interactions with other transcriptional components, and its impact on transcriptional regulation. Understanding the structural and biochemical properties of TAF13 is paramount for elucidating its precise role in transcriptional regulation and its broader implications in health and disease. Therefore, the research focused on TAF13 recombinant protein is pivotal in both basic biology and potential clinical applications, contributing to the broader understanding of transcriptional processes and the development of novel therapeutic strategies.
