Analytical Data
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基因名
ADAMTS7
- Application
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别名
ADAMTS7；A disintegrin and metalloProteinase with thrombospondin motifs 7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UKP4
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表达区间
242-593aa
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氨基酸序列
KWVETLVVADAKMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHADNTLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSCSINEDTGLPLAFTVAHELGHSFGIQHDGSGNDCEPVGKRPFIMSPQLLYDAAPLTWSRCSRQYITRFLDRGWGLCLDDPPAKDIIDFPSVPPGVLYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGTTCHSKLDAAVDGTRCGENKWCLSGECVPVGFRPEAVDGGWSGWSAWSICSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRLCNLQACP
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分子量
41.1kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ADAMTS7, a member of the A Disintegrin and Metalloproteinase with Thrombospondin Motifs (ADAMTS) family, has gained attention in biomedical research due to its involvement in various physiological and pathological processes, including cardiovascular diseases and arthritis. This secreted enzyme plays a significant role in the proteolytic processing of extracellular matrix components and interacts with growth factors and cytokines, influencing cellular behaviors such as migration, proliferation, and apoptosis. Recent studies have identified ADAMTS7 as a key player in the regulation of vascular remodeling and inflammation, linking it to the development of atherosclerosis and other vascular-related conditions. Genetic studies have also associated polymorphisms in the ADAMTS7 gene with the risk of coronary artery disease, underscoring its potential as a biomarker and therapeutic target. The recombinant protein expression of ADAMTS7 provides a valuable tool for elucidating its functional roles and mechanisms in disease, facilitating the identification of therapeutic strategies to modulate its activity. By investigating ADAMTS7 through recombinant protein studies, researchers can better understand its contributions to pathophysiological processes, paving the way for innovative approaches to combat cardiovascular-related disorders and improve patient outcomes.
